By using First Person Mode, it was possible to destroy him faster using RYNO II and firing at his chest. Around 200 ammo of RYNO II (two complete magazines) were needed to kill him, so the player had to move around the battlefield to collect ammo for RYNO II.
It is also possilbe to kill him with just the Tankbot Glove. Simply move behind a corner of a building. if you positioned yourself correctly he will be unable to do any damage to you as his shots will all simply hit the building. while he's distracted pull out your Tank Bot. Steer it right next to the giganto bot's leg then hold down the laser shooting button and fire the TankBots missiles as fast as you can. Do this until the timer runs out and then simply repeat the process. You should only have to do this about 6 times (5 times if acid mod is installed)
Another tactic that can make the battle far easier is simply shooting him with the turrets and exiting them before the seeking missiles hit you. This will prevent you from taking any damage.
- The Giganto Mech is the second biggest boss in the game series so far, only the Biobliterator being bigger.
- The Giganto Mech is one of the only boss enemies fought in Going Commando that did not receive an entry in the title's in-game Monsterpedia.
- Ratchet & Clank: Going Commando (first appearance)