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The Secret Laboratory was located under an opera house on planet Venantonio. It was an old Nefarious lab, where he created the dreaded Amoeboids (in the main series they were made on Rilgar. When Clank explored the laboratory, it was a wreck as Amoeboids had overran the lab. One thing Clank found odd in one part of the laboratory was a containment field holding Amoeboids in suspended animation, a plaque that was read told that it was an organic lifeform containment field. Sludge Slinders and Trash Drones patrolled the labs as well. This laboratory was where Clank found an experimental suitcase flamethrower - the Blowtorch Briefcase.